Rabbit Polyclonal antibody to PDCD2 (programmed cell death 2)This gene encodes a nuclear protein expressed in a variety of tissues. The rat homolog, Rp8, is transiently expressed in immature thymocytes and is thought to be involved in programmed cell death. Expression of the human gene has been shown to be repressed by BCL6, a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on PDCD2. This gene is closely linked on chromosome 6 to the gene for TBP, the TATA binding protein. Two transcripts encoding different proteins have been identified. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human PDCD2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Pig, BovineMouse (82%), Rat (81%), Pig (85%), Bovine (86%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
MGC12347 antibody, RP8 antibody, ZMYND7 antibody, PDCD2 antibody, programmed cell death protein 2 antibody, zinc finger protein Rp-8 antibody, zinc finger MYND domain-containing protein 7 antibody, programmed cell death 2 antibody
Molecular Weight(MW)
39 kDa (note) (6)
Cellular Localization
Nucleus
Application
Application
Sample (30 ug of whole cell lysate) A: H1299 B: HCT116 10% SDS PAGE diluted at 1:1000
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.