| Product Name | PDE4A4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to PDE4A4The PDE4 family of cAMP-specific phosphodiesterases represents an important therapeutic and pharmacological target for their anti-inflammatory and anti-depressant effects. Four distinct genes (PDE4A, PDE4B, PDE4C and PDE4D), encode large family of PDE4 isoforms. Almost all of these isoforms have a common core made up of central catalytic domain and C-terminal tail. |
| Immunogen | N-terminus PDE4A4 synthetic cyclic peptide. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIPWB |
| ICC: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/500. Detects a band of approximately 125 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseRabbit |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | Phosphodiesterse Type 4A4 |
|---|---|
| Target | PDE4A4 |
| Tissue Specificity | Does not cross react with PDE4A1, A8 or A5 proteins and PDE4B, PDE4C and PDE4D or with other PDE family members. |
| Positive Control | U937 cells, human SHSY-5Y and Jurkat cell extracts |
|---|---|
| Application Notes | ICC: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/500. Detects a band of approximately 125 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.02% Thimerosal / Merthiolate |
