Application
Application| Product Name | PDE6G antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to PDE6 gammaCyclic GMP-phosphodiesterase plays a key role in the normal functioning of retinal rod photoreceptor cells. The enzyme is composed of alpha- and beta-catalytic subunits which are inhibited by 2 identical gamma subunits. The PDE6 gamma subunit has been cloned and sequenced from human retina. The 1,012-bp cDNA had a coding region of 261 bp that was highly homologous to those of the corresponding cDNA from bovine and mouse retinas. Comparison of the deduced amino acid sequences from 3 species indicated evolutionary conservation. |
| Immunogen | Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (C terminal). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: Use at a dilution of 1/500. Detects a band of approximately 11 kDa (predicted molecular weight: 10 kDa). Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PDE 6 PDEG Phosphodiesterase 6G cGMP Specific Retinal Rod Photoreceptor cGMP Phosphodiesterase gamma |
|---|---|
| Target | PDE6G |
| Tissue Specificity | This antibody does not cross-react with the other PDE6 subunits or with other PDE family members. |
Application
Application| Application Notes | WB: Use at a dilution of 1/500. Detects a band of approximately 11 kDa (predicted molecular weight: 10 kDa). Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.02% Sodium Azide |
