| Product Name | PDE7A antibody, C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to PDE7ACyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3’, 5’-monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE7 enzyme belongs to a family of cAMP-dependent PDEs that provide the major means of inactivating the key intracellular second messenger, cAMP. Two genes (PDE7A and PDE7B) encode the PDE7 family, each with multiple splice variants |
| Immunogen | Designed from the C-terminal region common to the 7A isoform |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCIPWB |
| For WB: Use at 1:2000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HCP1 PDE7 |
|---|---|
| Target | PDE7A |
| Tissue Specificity | The antibody selectively detects proteins corresponding to the PDE7A1 isoform, in human, mouse & rat |
| Cellular Localization | PDE7A1 (57 kDa) is located mostly to soluble cellular fractions. PDE7A2 (50 kDa) is located to particulate cellular fractions. |
| Application Notes | For WB: Use at 1:2000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 2-8°C. For extended storage, aliquot and store at -20°C. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | Diluted serum |
