Application
Sample (30 ug of whole cell lysate) A: A549 5% SDS PAGE diluted at 1:1000| Product Name | PDZK3 antibody , N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to PDZK3 (PDZ domain containing 2)Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human PDZK3. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, RatMouse (92%), Rat (92%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | AIPC antibody KIAA0300 antibody PAPIN antibody PDZK3 antibody PIN1 antibody PDZD2 antibody PDZ domain containing 3 antibody PDZ domain-containing protein 3 antibody activated in prostate cancer protein antibody PDZ domain-containing protein 2 anti |
|---|---|
| Target | PDZK3 |
| Molecular Weight(MW) | 302 kDa (note) |
| Cellular Localization | Nucleus (By similarity) , Cytoplasm , Endoplasmic reticulum , Processed PDZ domain-containing protein 2: Secreted |
Application
Sample (30 ug of whole cell lysate) A: A549 5% SDS PAGE diluted at 1:1000| Positive Control | A549 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
