Application
WB analysis of extracts from various cells using Pepsinogen C antibody.Application
IHC-P analysis of human ovarian cancer tissue using Pepsinogen C antibody.Application
IHC-P analysis of human rectal tissue using Pepsinogen C antibody at a dilution of 1:200.Application
IHC-P analysis of human stomach cancer using Pepsinogen C antibody at a dilution of 1:200.| Product Name | Pepsinogen C antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Pepsinogen CThis gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009] |
| Immunogen | Fusion protein of human PGC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| WB: 1:500 - 1:2000. IHC: 1:50 - 1:100: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PGC PEPC PGII progastricsin (pepsinogen C) |
|---|---|
| Target | Pepsinogen C |
| Molecular Weight(MW) | 42 kDa (note) |
Application
WB analysis of extracts from various cells using Pepsinogen C antibody.
Application
IHC-P analysis of human ovarian cancer tissue using Pepsinogen C antibody.
Application
IHC-P analysis of human rectal tissue using Pepsinogen C antibody at a dilution of 1:200.
Application
IHC-P analysis of human stomach cancer using Pepsinogen C antibody at a dilution of 1:200.| Application Notes | WB: 1:500 - 1:2000. IHC: 1:50 - 1:100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
