| Product Name | Peripherin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [2Q135] to PeripherinPeripherin is a Class III intermediate filament subunit found in both the peripheral and central nervous systems, though it is concentrated, as its name suggests, in the neurons of peripheral ganglia and their processes. Antibodies to peripherin can be used in identifying, classifying, and studying neurons in the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig?s disease and some neuronally derived tumors. Peripherin is also a major component of the cytoskeleton of PC12 cells, widely used model system for studies of neuronal differentiation. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes. Peripherin is not related to peripherin-RDS, a photoreceptor protein associated with retinal degeneration and blindness. |
| Immunogen | Electrophoretically pure trp-E-peripherin fusion protein containing all but the 4 N-terminal amino acids of rat peripherin. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Clone Number | 2Q135 |
| Host Species | Mouse |
| Tested Applications | ICC/IFWB |
| ICC: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 54 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMousePigRatBovine |
| Concentration | 1mg/ml |
| Gene Synonyms | PRPH |
|---|---|
| Target | Peripherin |
| Application Notes | ICC: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 54 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: None. Constituents: Tissue culture supernatant |
