Application
staining Peroxiredoxin 4 in TSU-Pr1 cells.| Product Name | Peroxiredoxin 4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Peroxiredoxin 4The Peroxiredoxin (Prdx, Prx, or Trx-Px) family of enzymes is a recently identified family of peroxidases found in free-living organisms. The six known isoforms (Prx1-6) play an important role in protecting lipids, enzymes and DNA against peroxides, such as hydrogen peroxide. The ubiquitously expressed peroxiredoxins have also been shown to play a role in apoptosis and cell differentiation. This is acomplished by the active cysteine of Prx reducing peroxides, which is then converted into a transient cysteine sulfenic acid or cysteine sulfinic acid. If Prx protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer. |
| Immunogen | Antigen is purified human recombinant Peroxiredoxin 4 from K562 cells. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCWB |
| ICC/IF: 1:500: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Peroxiredoxin4 AOE372 PRDX4 PRX4 Thioredoxin Peroxidase (Antioxidant Enzyme) Thioredoxin peroxidase AO372 Peroxiredoxin 4 |
|---|---|
| Target | Peroxiredoxin 4 |
| Tissue Specificity | This antibody is specific for Peroxiredoxin 4 and shows no cross reactivity with other Peroxiredoxin isoforms. |
| Cellular Localization | Cytoplasmic |
Application
staining Peroxiredoxin 4 in TSU-Pr1 cells.| Positive Control | PC3 cell lysate (WB)TSU-Pr1 cells (ICC) |
|---|---|
| Application Notes | ICC/IF: 1:500: |
| Form | Liquid |
|---|---|
| Storage Instructions | store in -20, avoid freeze/thaw cycles. |
| Storage Buffer | Preservative: 0.05% Sodium Azide |
