Application
Western blot analysis of PFKFB2 (pS483) expression in HeLa H2O2-treated (A); SP2/0 H2O2-treated (B); H9C2 H2O2-treated (C) whole cell lysates.| Product Name | PFKFB2 (phospho Ser483) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to PFKFB2 (phospho Ser483)The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PFKFB2. The exact sequence is proprietary. |
| Modification | p-Ser483 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | 6-phosphofructo-2-kinase/fructose-2 6-biphosphatase 2 PFKFB2 PFK-2/FBPase-2 |
|---|---|
| Target | PFKFB2 (phospho Ser483) |
| Tissue Specificity | Recognizes endogenous levels of PFKFB2 (pS483) protein. |
Application
Western blot analysis of PFKFB2 (pS483) expression in HeLa H2O2-treated (A); SP2/0 H2O2-treated (B); H9C2 H2O2-treated (C) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
