| Product Name | Phospholamban (phospho Ser16) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Phospholamban ( phospho S16 )Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases; whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer. |
| Immunogen | KLH-conjugated, synthetic peptide corresponding to amino acids 14-25 of human cardiac phospholamban (RA[pS]TIEMPQQAR-C) with an added C-terminal cysteine. The immunizing sequence is identical in mouse, rat, rabbit, pig and dog. |
| Modification | p-Ser16 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: Use at a concentration of 0.5 - 2 μg/ml. Predicted molecular weight: 5-25 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseDogPigRatRabbitBovine |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CMD1P PLB Phospholamban (phospho S16) Phospholamban (phospho Ser16) Phospholamban (pS16) Phospholamban (pSer16) Phospholamban phospho S16 Phospholamban phospho Ser16 Phospho Phospholamban (S16) Phospho Phospholamban (Ser16) Phospho Phospholamban |
|---|---|
| Target | Phospholamban |
| Cellular Localization | Membrane |
| Positive Control | Bovine cardiac preparation |
|---|---|
| Application Notes | WB: Use at a concentration of 0.5 - 2 μg/ml. Predicted molecular weight: 5-25 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for 2 years at -20 degrees Celcius from the date of shipment. |
| Storage Buffer | Preservative: 0.05% Sodium Azide; Constituents: 30% Glycerol, 0.2M Tris glycine, 0.15M Sodium chloride |
