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PHOX2A antibody

Catalog Number:OM268452
OM268452
Discount Price
OM268452-100ul
1~2 Week
100ul
OM268452-50ul
50ul
OM268452-20ul
20ul
1~2 Week
Product Profile
Product Name PHOX2A antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to PHOX2AThe protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008]
Immunogen PHOX2A antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human PHOX2A.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISAICC/IFIHC-PWB
WB: 1 ug/ml. IHC: 2.5 ug/ml. IF: 2.5 ug/ml:
Species Reactivity HumanRat
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms NCAM2
paired-like homeobox 2a
ARIX
FEOM2
PMX2A
CFEOM2
Target PHOX2A
Tissue Specificity PHOX2A antibody is predicted to not cross-react with other paired homeobox family members.
Application

Application

Western blot analysis of PHOX2A in rat brain tissue lysate with PHOX2A antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.

Application

Immunohistochemistry of PHOX2A in human brain tissue with PHOX2A antibody at 2.5 μg/mL.

Application

Immunofluorescence of PHOX2A in human brain tissue with PHOX2A antibody at 20 μg/mL.
Application Notes WB: 1 ug/ml. IHC: 2.5 ug/ml. IF: 2.5 ug/ml:
Additional Information
Form Liquid
Storage Instructions Stored At 4ºc For Three Months And -20ºc, Stable For Up To One Year. As With All Antibodies Care Should Be Taken To Avoid Repeated Freeze Thaw Cycles. Antibodies Should Not Be Exposed To Prolonged High Temperatures.
Storage Buffer PBS containing 0.02% sodium azide.
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