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PKC epsilon antibody

Catalog Number:OM268721
OM268721
Discount Price
OM268721-100ul
1~2 Week
100ul
OM268721-50ul
50ul
OM268721-20ul
20ul
1~2 Week
Product Profile
Product Name PKC epsilon antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to PKC epsilonProtein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSe
Immunogen Recombinant protein of human PRKCE
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICC/IFIHCIHC-PWB
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, ICC: 1:50 - 1:200
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms nPKC epsilon , protein kinase C epsilon , PRKCE , PKCE
Target PKC epsilon
Application

Application

Western blot analysis of extracts of various cell lines, using PRKCE antibody.

Application

Immunohistochemistry of paraffin-embedded rat spleen using PRKCE antibody at dilution of 1:200 (x400 lens).

Application

Immunohistochemistry of paraffin-embedded human colon using PRKCE antibody at dilution of 1:200 (x400 lens).

Application

Immunohistochemistry of paraffin-embedded human esophageal cancer using PRKCE antibody at dilution of 1:200 (x400 lens).

Application

Immunohistochemistry of paraffin-embedded Human gastric using PRKCE antibody at dilution of 1:100 (x400 lens).

Application

Immunohistochemistry of paraffin-embedded Human kidney using PRKCE antibody at dilution of 1:100 (x400 lens).
Application Notes WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, ICC: 1:50 - 1:200
Additional Information
Form Liquid
Storage Instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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