Application
Western blot analysis of PLAC1 in human placenta tissue lysate with PLAC1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.Application
Immunofluorescence of PLAC1 in Hela cells with PLAC1 antibody at 20 ug/mL.Application
Immunocytochemistry of PLAC1 in HeLa cells with PLAC1 antibody at 10 μg/mL.| Product Name | PLAC1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to PLAC1PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer. |
| Immunogen | A synthetic peptide encompassing a sequence within the 130 - 180 a.a. of human PLAC1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFWB |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Placentaspecific protein 1, Placentaspecific protein1, CT92, PLAC1, Placenta-specific protein 1, Placenta specific protein 1 |
|---|---|
| Target | PLAC1 |
Application
Western blot analysis of PLAC1 in human placenta tissue lysate with PLAC1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Application
Immunofluorescence of PLAC1 in Hela cells with PLAC1 antibody at 20 ug/mL.
Application
Immunocytochemistry of PLAC1 in HeLa cells with PLAC1 antibody at 10 μg/mL.| Positive Control | Blocking Peptide: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
