Application
Western blot analysis of extracts from HeLa cells, using KLKB1 (heavy chain,Cleaved-Arg390) Antibody. The lane on the right is treated with the synthesized peptide.| Product Name | Plasma Kallikrein 1B (cleaved Arg390) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Plasma Kallikrein 1B (cleaved Arg390)The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Plasma Kallikrein 1B. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ELISA: 1:10000 Optimal dilutions should be determined experimentally by the end user. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | KLK3, PPK, KLKB1, KLKB1 (cleaved R390), KLKB1 (cleaved Arg390), KLKB1 cleaved R390, KLKB1 cleaved Arg390, Cleaved KLKB1 (R390), Cleaved KLKB1 (Arg390) |
|---|---|
| Target | Plasma Kallikrein 1B |
| Molecular Weight(MW) | 45 kDa (note) |
| Tissue Specificity | Plasma Kallikrein 1B (heavy chain,Cleaved-Arg390) Antibody detects endogenous levels of fragment of activated KLKB1 resulting from cleavage adjacent to Arg390. |
Application
Western blot analysis of extracts from HeLa cells, using KLKB1 (heavy chain,Cleaved-Arg390) Antibody. The lane on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:10000 Optimal dilutions should be determined experimentally by the end user. |
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| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
