| Product Name | PLK1 (phospho Ser482/486/490) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to PLK1 (phospho Ser482/486/490)Plays multiple essential roles during mitosis. Phosphorylates the amino-terminal domain of cdc25, which leads to cyclin b-cdc2 activation and mitotic entry. Also required for organization of bipolar spindles, and for exit from mitosis. Phosphorylates tpx2. |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser482/486/490 conjugated to KLH |
| Modification | p-Ser482/486/490 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Xenopus |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PLK, PLK1, STPK13, PLK1 (phospho S482/S486/S490), PLK1 (phospho Ser482/Ser486/Ser490), PLK1 (pS482/pS486/pS490), PLK1 (pSer482/pSer486/pSer490), PLK1 phospho S482/S486/S490, PLK1 phospho Ser482/Ser486/Ser490, Phospho PLK1 (S482/S486/S490), Phospho PLK1 (Se |
|---|---|
| Target | PLK1 (phospho Ser482/486/490) |
| Molecular Weight(MW) | 120 (note) |
| Cellular Localization | Localized at centrosomes at prophase, spindles at metaphase, and at the midbody during cytokinesis. |
| Form | Liquid |
|---|---|
| Storage Instructions | For long-term storage, aliquot and store at -20 C. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
