Rabbit Polyclonal antibody to PMEPA1This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Immunogen
PMEPA1 antibody was raised against a 16 amino acid peptide near the center of human PMEPA1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
WB: 1 - 2 ug/ml:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
TMEPAI STAG1 prostate transmembrane protein androgen induced 1
Target
PMEPA1
Tissue Specificity
PMEPA1 antibody is human, mouse and rat reactive. At least four isoforms are known to exist; this antibody will detect all of the isoforms.
Application
Application
Western blot analysis of PMEPA1 inA549 cell lysate with PMEPA1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Application Notes
WB: 1 - 2 ug/ml:
Additional Information
Form
Liquid
Storage Instructions
PMEPA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Storage Buffer
PMEPA1 antibody is supplied in PBS containing 0.02% sodium azide.