Rabbit Polyclonal antibody to PMM2 (phosphomannomutase 2)The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human PMM2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Chicken, Rhesus Monkey, BovineMouse (93%), Rat (95%), Chicken (86%), Rhesus Monkey (98%), Bovine (93%)