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PMS1 antibody

Catalog Number:OM269089
OM269089
Discount Price
OM269089-100ul
1~2 Week
100ul
OM269089-50ul
50ul
OM269089-20ul
20ul
1~2 Week
Product Profile
Product Name PMS1 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to PMS1 (PMS1 postmeiotic segregation increased 1 (S. cerevisiae))This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the center region of human PMS1. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IPWB
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity Human
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms HNPCC3
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PMSL1
hPMS1
Target PMS1
Molecular Weight(MW) 106 kDa (note) (10)
Cellular Localization Nucleus
Application

Application

PMS1 antibody detects PMS1 protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 5 % SDS-PAGE, and blotted with PMS1 antibody diluted by 1:1000

Application

Immunoprecipitation of PMS1 protein from HeLa whole cell extracts using 5 μg of PMS1 antibody . Western blot analysis was performed using PMS1 antibody . EasyBlot anti-Rabbit IgG was used as a secondary reagent.
Positive Control 293T, A431, HeLa, HepG2
Application Notes *Optimal dilutions/concentrations should be determined by the researcher. :
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
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