Rabbit Polyclonal antibody to PNRThe photoreceptor-specific nuclear receptor (PNR) is a recently identified nuclear transcription factor.? PNR expression pattern appears to be restricted in the retina, specific to photoreceptor cells.? PNR has been shown to share structural similarity with TLX, an orphan receptor.? Despite distinct differences in the DNA binding domain, studies have shown that PNR is capable of recognizing a subset of TLX target sequences in vitro.? Recent studies suggest that PNR plays a support role in the regulation of signaling pathways intrinsic to the photoreceptor cell function. The corresponding gene for the PNR is NR2E3.
Immunogen
Synthetic peptide corresponding to residues R(392) K T I G N T P M E K L L C D M F K N(410) of human PNR.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
WB: 2 ug/ml Optimal dilution / concentration should be determined by the end user.:
Species Reactivity
HumanRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
Nr2e3 A930035N01Rik PNR RNR rd7 nuclear receptor subfamily 2 group E member 3
Target
PNR
Application
Application
WB analysis of rat eye extracts using PNR antibody.
Application Notes
WB: 2 ug/ml Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
PBS containing 1 mg/ml BSA and 0.05% sodium azide.