Rabbit Polyclonal antibody to Pokemon (zinc finger and BTB domain containing 7A)Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Pokemon. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
DKFZp547O146 antibody FBI-1 antibody FBI1 antibody LRF antibody MGC99631 antibody ZBTB7 antibody ZNF857A antibody pokemon antibody ZBTB7A antibody factor that binds to inducer of short transcripts protein 1 antibody TIP21 antibody factor binding
Molecular Weight(MW)
61 kDa (note) (2)
Cellular Localization
Nucleus
Application
Application
Immunohistochemical analysis of paraffin-embedded human lung, using Pokemon antibody at 1:100 dilution.
Application
Sample (30 ug of whole cell lysate) A: Hep G2 7.5% SDS PAGE diluted at 1:1000
Positive Control
HeLa , HepG2
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.