Rabbit Polyclonal antibody to POLR3KThis gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17.[provided by RefSeq, Jul 2010]
Immunogen
Recombinant protein of human POLR3K
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB 1:500 - 1:2000, IHC 1:50 - 1:200:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
RPC11 hRPC11 RPC12.5 polymerase (RNA) III (DNA directed) polypeptide K 12.3 kDa C11-RNP3 RPC10 My010 C11
Target
POLR3K
Molecular Weight(MW)
12 kDa (note)
Application
Application
Western blot analysis of extracts of various cell lines, using POLR3K antibody.