Rabbit Polyclonal antibody to PORThis gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human POR
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB 1:500 - 1:2000, IHC 1:50 - 1:100:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
CYPOR P450 (cytochrome) oxidoreductase P450R CPR
Target
POR
Molecular Weight(MW)
77 kDa (note)
Application
Application
Western blot analysis of extract of various cells, using POR antibody.
Application
Immunohistochemistry of paraffin-embedded human esophagus using POR antibody at dilution of 1:100 (40x lens).