Rabbit polyclonal antibody to PP14CInhibitor of PPP1CA. Has over 600-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
Immunogen
The antiserum was produced against synthesized peptide derived from human PPP1R14C.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
ELISA: 1:20000Optimal dilutions should be determined experimentally by the end user.:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
PKC-potentiated PP1 inhibitory protein PP14C Serologically defined breast cancer antigen NYBR81 PKCpotentiated PP1 inhibitory protein Kinase-enhanced PP1 inhibit Kinaseenhanced PP1 inhibit Kinaseenhanced PP1 inhibitor Serologically defined breast ca
Target
PP14C
Molecular Weight(MW)
17 kDa (note)
Tissue Specificity
PPP1R14C Antibody detects endogenous levels of total PPP1R14C protein.
Application
Application
Western blot analysis of extracts from Jurkat/COLO205 cells, using PPP1R14C Antibody. The lane on the right is treated with the synthesized peptide.
Application Notes
ELISA: 1:20000Optimal dilutions should be determined experimentally by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at -20 degrees Celcius. Product is stable for at least 1 year.
Storage Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.