Rabbit polyclonal antibody to PPP1R3CActs as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types.
Immunogen
The antiserum was produced against synthesized peptide derived from human PPP1R3C.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
ELISA: 1:20000Optimal dilutions should be determined experimentally by the end user.:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
PPP1R3C Protein targeting to glycogen R5 Protein phosphatase 1 regulatory subunit 5 Protein phosphatase1 regulatory subunit5 PTG
Target
PPP1R3C
Molecular Weight(MW)
36 kDa (note)
Tissue Specificity
PPP1R3C Antibody detects endogenous levels of total PPP1R3C protein.
Application
Application
Western blot analysis of extracts from HepG2/HeLa/COS7 cells, using PPP1R3C Antibody. The lane on the right is treated with the synthesized peptide.
Application Notes
ELISA: 1:20000Optimal dilutions should be determined experimentally by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at -20 degrees Celcius. Product is stable for at least 1 year.
Storage Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.