Application
Western blot analysis of lysed extracts from mouse brain tissue using α-Synuclein (Phospho-Ser129).| Product Name | a Synuclein (phospho Ser129) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PD1, NACP, PARK1, PARK4, ERBB, ERBB1, HER1, SYN, SYUA |
| Product description | May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.1) Takahashi T, et al. J Biol Chem 2003 Oct 24; 278 (43): 42225-33Ahn BH, et al. J Biol Chem 2002 Apr 05; 277 (14): 12334-42Negro A, et al. FASEB J 2002 Feb; 16 (2): 210-2Goldberg, et al. Nat. Cell Biol. 2000; 2, 115-119. |
| Immunogen | a-Synuclein (Phospho-Ser129) antibody was raised against a peptide sequence around phosphorylation site of serine 129 (M-P-S (p) -E-E) derived from Human α-Synuclein. |
| Modification | p-Ser129 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SNCA |
|---|---|
| Alternative Names | PD1 NACP PARK1 PARK4 ERBB ERBB1 HER1 SYN SYUA |
| Molecular Weight(MW) | 18 kDa |
| Tissue Specificity | This antibody detects endogenous level of VEGFR2 only when phosphorylated at tyrosine 1214. |
| Entrez Gene | 6622 |
|---|---|
| Protein Accession | NP_000336.1 |
Application
Western blot analysis of lysed extracts from mouse brain tissue using α-Synuclein (Phospho-Ser129).| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
