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Rabbit anti-SNCA polyclonal antibody - middle region

Catalog Number:OM110856
OM110856
Discount Price
OM110856-100ul
1~2 Week
100ul
OM110856-50ul
50ul
OM110856-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-SNCA polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias MGC110988, NACP, PARK1, PARK4, PD1
Immunogen The immunogen for anti-SNCA antibody: synthetic peptide directed towards the middle region of human SNCA
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHorsePigSheep
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol SNCA
Gene Synonyms MGC110988
NACP
PARK1
PARK4
PD1
Gene Full Name Synuclein, alpha (non A4 component of amyloid precursor)
Gene Summary Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease.Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Two alternatively spliced transcripts of SNCA have been identified. Additional splicing may be present but the full-length nature of these variants has not been determined.
Alternative Names MGC110988
NACP
PARK1
PARK4
PD1
Molecular Weight(MW) 11kDa
Sequence 112 amino acids
Database Links
Entrez Gene 6622
SwissProt ID P37840-2
Protein Accession NP_009292
Application

Western blot

Host: Rabbit Target Name: NSUN6 Sample Tissue: Human Fetal Lung Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: FAM46C Sample Tissue: Human Fetal Liver Antibody Dilution: 1.0ug/ml

Western blot

0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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