Application
Antibody used in IHC on Human kidney.Application
Antibody used in WB on Human HepG2 at 1.25 ug/ml.| Product Name | AADAT Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AADAT, KAT2, KATII |
| Product description | AADAT is a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties.This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist.1) Goh, D.L., (2002) Mol. Genet. Metab. 76 (3), 172-180. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AADAT. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| AADAT antibody can be used for detection of AADAT by ELISA at 1:1562500. AADAT antibody can be used for detection of AADAT by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | AADAT |
|---|---|
| Alternative Names | AADAT KAT2 KATII |
| Molecular Weight(MW) | 47 kDa, 47 kDa |
Application
Antibody used in IHC on Human kidney.
Application
Antibody used in WB on Human HepG2 at 1.25 ug/ml.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | AADAT antibody can be used for detection of AADAT by ELISA at 1:1562500. AADAT antibody can be used for detection of AADAT by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store AADAT antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
