Application
Western blot analysis in HepG2,Y79 cell line lysates (35ug/lane).| Product Name | AADAT Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial, KAT/AadAT, 2-aminoadipate aminotransferase, 2-aminoadipate transaminase, Alpha-aminoadipate aminotransferase, AadAT, Kynurenine aminotransferase II, Kynurenine--oxoglutarate aminotransferase II |
| Product description | This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist.1) Han, Q., et al. Biosci. Rep. 28(4):205-215(2008) |
| Immunogen | This AADAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the Central region of human AADAT. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | AADAT |
|---|---|
| Alternative Names | Kynurenine/alpha-aminoadipate aminotransferase mitochondrial KAT/AadAT 2-aminoadipate aminotransferase 2-aminoadipate transaminase Alpha-aminoadipate aminotransferase AadAT Kynurenine aminotransferase II Kynurenine--oxoglutarate aminotransferase II |
| Molecular Weight(MW) | 47 kDa |
Application
Western blot analysis in HepG2,Y79 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
