Application
Western blot analysis of AANAT Antibody in Y79 cell line lysates (35ug/lane)| Product Name | AANAT Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Serotonin N-acetyltransferase, Serotonin acetylase, Aralkylamine N-acetyltransferase, AA-NAT, AANAT, SNAT |
| Product description | AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.1) Mansour, H.A., et al. Bipolar Disord 11(7):701-710(2009) |
| Immunogen | This AANAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human AANAT. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | AANAT |
|---|---|
| Alternative Names | Serotonin N-acetyltransferase Serotonin acetylase Aralkylamine N-acetyltransferase AA-NAT AANAT SNAT |
| Molecular Weight(MW) | 23 kDa |
Application
Western blot analysis of AANAT Antibody in Y79 cell line lysates (35ug/lane)| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
