Histo-blood group ABO system transferase, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactosi
Product description
This gene encodes proteins related to the first discovered
blood group system, ABO. Which allele is present in an individual
determines the blood group. The 'O' blood group is caused by a
deletion of guanine-258 near the N-terminus of the protein which
results in a frameshift and translation of an almost entirely
different protein. Individuals with the A, B, and AB alleles
express glycosyltransferase activities that convert the H antigen
into the A or B antigen. Other minor alleles have been found for
this gene.1) Thuresson, B., et al. Transfusion 48(3):493-504(2008)
Immunogen
This ABO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human ABO.
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.