Application
Western blot analysis in human normal Uterus tissue lysates (35ug/lane).Application
ABRA Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.| Product Name | ABRA Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Actin-binding Rho-activating protein, Striated muscle activator of Rho-dependent signaling, STARS, ABRA {ECO:0000312|EMBL:AAI051061} |
| Product description | ABRA acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling (By similarity).1) Lamon, S., et al. J. Physiol. (Lond.) 587 (PT 8), 1795-1803 (2009)Kuwahara, K., et al. J. Clin. Invest. 117(5):1324-1334(2007) Kuwahara, K., et al. Mol. Cell. Biol. 25(8):3173-3181(2005) Arai, A., et al. J. Biol. Chem. 277(27):24453-24459(2002) Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000) |
| Immunogen | This ABRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-304 amino acids from the C-terminal region of human ABRA. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ABRA |
|---|---|
| Alternative Names | Actin-binding Rho-activating protein Striated muscle activator of Rho-dependent signaling STARS ABRA {ECO:0000312|EMBL:AAI051061} |
| Molecular Weight(MW) | 43 kDa |
Application
Western blot analysis in human normal Uterus tissue lysates (35ug/lane).
Application
ABRA Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
