| Product Name | Activin Receptor IIB Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Activin Receptor IIB (ACTR-IIB) is a transmembrane receptor that forms an activin receptor complex with activin type-1 receptors (ACVR1, ACVR1B or ACVR1c). ACTR-IIB transduces the activin signal from the cell surface to the cytoplasm and regulates therefore many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary. |
| Immunogen | Recombinant extracellular domain (ecd) of mouse activin receptor IIB. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ELISA: (1:400) . Western Blot: (1:5000) . Optimal conditions must be determined individually for each application. | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Acvr2b |
|---|---|
| Alternative Names | ACVR2B ACTR-IIB Activin receptor type-2B |
| Tissue Specificity | Recognizes the extracellular domain of human and mouse ACTR-IIB. Does not cross-react with related human proteins ActR-IIecd, BMPR-IIecd, BMPR-IAecd, BMPR-IBecd or ActR-Iecd. |
| Application Notes | ELISA: (1:400) . Western Blot: (1:5000) . Optimal conditions must be determined individually for each application. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least 1 year after receipt when stored at -20˚C. |
| Storage Buffer | Liquid. In PBS with 1 mg/ml BSA and 0.02% sodium azide. |
