This gene encodes a member of the ADAM (a disintegrin and
metalloprotease) protein family. Members of this family are
membrane-anchored proteins structurally related to snake venom
disintegrins, and have been implicated in a variety of biological
processes involving cell-cell and cell-matrix interactions,
including fertilization, muscle development, and neurogenesis. This
gene represents a candidate tumor supressor gene for human breast
cancer based on its location within a minimal region of chromosome
17q21 previously defined by tumor deletion mapping. [provided by
RefSeq].1) Fu, G.K., et al. Genomics 84(1):205-210(2004)
Immunogen
This ADAM11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the N-terminal region of human ADAM11.
Disintegrin and metalloproteinase domain-containing protein 11 ADAM 11 Metalloproteinase-like disintegrin-like and cysteine-rich protein MDC ADAM11 MDC
Western Blot at 1:500 dilution + CCRF-CEM whole cell lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:500
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.