This gene encodes a member of the ADAM (a disintegrin and
metalloprotease domain) family. Members of this family are
membrane-anchored proteins structurally related to snake venom
disintegrins, and have been implicated in a variety of biological
processes involving cell-cell and cell-matrix interactions,
including fertilization, muscle development, and neurogenesis. This
gene is highly expressed in the brain and may function as an
integrin ligand in the brain.1) Pan, Q., et al. Biochem. Biophys. Res. Commun. 401(2):306-312(2010)
Immunogen
This ADAM23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 803-831 amino acids from the C-terminal region of human ADAM23.
Disintegrin and metalloproteinase domain-containing protein 23 ADAM 23 Metalloproteinase-like disintegrin-like and cysteine-rich protein 3 MDC-3 ADAM23 MDC3
Molecular Weight(MW)
92 kDa
Sequence Similarities
Predicted species reactivity based on immunogen sequence: Mouse
Western blot analysis in A2058 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.