Application
Immunohistochemistry staining of ADAMTS4 in heart tissue using ADAMTS4 Antibody.| Product Name | ADAMTS4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADAMTS4, ADAMTS-2, ADAMTS-4, ADAM-TS 4, ADAM-TS4, ADMP-1, Aggrecanase-1, KIAA0688 |
| Product description | ADAMTS4, also known as aggrecanase-1, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan and the brain extracellular matrix proteoglycan brevican. The ADAMTS4 protein contains a signal sequence, a propeptide domain, a catalytic domain, a disintegrin-like motif, and a C-terminal domain with a thrombospondin (TSP) type 1 motif. ADAMTS4 has been implicated in inflammatory joint diseases, and it also may be a factor in the progression of glioma and Alzheimer's disease. |
| Immunogen | ADAMTS4 antibody was raised against a peptide located near the internal domain of ADAMTS4 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| ADAMTS4 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, immunofluorescence starting at 10 μg/mL, and immunoprecipitation.: |
|
| Species Reactivity | BatDogGibbonHorseHumanMonkeyOrangutan |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ADAMTS4 |
|---|---|
| Alternative Names | ADAMTS4 ADAMTS-2 ADAMTS-4 ADAM-TS 4 ADAM-TS4 ADMP-1 Aggrecanase-1 KIAA0688 |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ADAMTS8 (53%). |
Application
Immunohistochemistry staining of ADAMTS4 in heart tissue using ADAMTS4 Antibody.| Application Notes | ADAMTS4 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, immunofluorescence starting at 10 μg/mL, and immunoprecipitation.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store ADAMTS4 antibody at 4 ˚C for short term applications. For long term storage, aliquot and -20 ˚C. |
| Storage Buffer | PBS, 0.1% sodium azide. |
