This gene is a member of the ADAR (adenosine deaminase
acting on RNA) family. Using site-specific adenosine modification,
proteins encoded by these genes participate in the pre-mRNA editing
of nuclear transcripts. The protein encoded by this gene,
tRNA-specific adenosine deaminase 1, is responsible for the
deamination of adenosine 37 to inosine in eukaryotic tRNA.
Alternatively spliced transcript variants have been described.1) Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)
Immunogen
This ADAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-60 amino acids from the N-terminal region of human ADAT1.
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.