The protein encoded by this gene is an adenosine receptor
that belongs to the G-protein coupled receptor 1 family. There are
3 types of adenosine receptors, each with a specific pattern of
ligand binding and tissue distribution, and together they regulate
a diverse set of physiologic functions. The type A1 receptors
inhibit adenylyl cyclase, and play a role in the fertilization
process. Animal studies also suggest a role for A1 receptors in
kidney function and ethanol intoxication. Transcript variants with
alternative splicing in the 5' UTR have been found for this gene.1) Lane, J.R., et al. Biochem. Pharmacol. 80(8):1180-1189(2010)
Immunogen
This ADORA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the C-terminal region of human ADORA1.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.