| Product Name | Prekallikrein + Kallikrein antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [13G11] to Prekallikrein/KallikreinThis gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Immunogen | Purified human prekallikrein. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 13G11 |
| Host Species | Mouse |
| Tested Applications | ELISAInhibitionWB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanBaboonChimpanzeeRhesus Monkey |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | PKK PPK KLK3 PKKD |
|---|---|
| Target | Prekallikrein + Kallikrein |
| Tissue Specificity | This antibody recognizes two variants (88 kd and 85 kd) of prekallikrein and kallikrein. |
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS, pH7.2 |
