Application
PRELP antibody detects PRELP protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with PRELP antibody diluted at 1:500.Application
PRELP antibody detects PRELP protein at secreted on mouse prostate by immunohistochemical analysis. Sample: Paraffin-embedded mouse prostate. PRELP antibody dilution: 1:500.Application
PRELP antibody detects PRELP protein at secreted on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. PRELP antibody dilution: 1:500.| Product Name | PRELP antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to PRELP (proline/arginine-rich end leucine-rich repeat protein)The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human PRELP. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Mouse |
| Predicted Reactivity | Human, Rat, Rhesus Monkey, BovineHuman (100%), Rat (91%), Rhesus Monkey (99%), Bovine (91%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | proline/arginine-rich end leucine-rich repeat protein MSTP161 SLRR2A MST161 |
|---|---|
| Target | PRELP |
| Molecular Weight(MW) | 44 kDa (note) (3) |
| Cellular Localization | Secreted , extracellular space , extracellular matrix |
Application
PRELP antibody detects PRELP protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with PRELP antibody diluted at 1:500.
Application
PRELP antibody detects PRELP protein at secreted on mouse prostate by immunohistochemical analysis. Sample: Paraffin-embedded mouse prostate. PRELP antibody dilution: 1:500.
Application
PRELP antibody detects PRELP protein at secreted on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. PRELP antibody dilution: 1:500.| Positive Control | mouse heart |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
