Rabbit Polyclonal antibody to PRG2The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Immunogen
Recombinant protein of human PRG2
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
MBP1 BMPG proteoglycan 2 bone marrow (natural killer cell activator eosinophil granule major basic protein) MBP
Target
PRG2
Molecular Weight(MW)
25 kDa (note)
Application
Application
Immunohistochemistry of paraffin-embedded Human gastric using PRG2 antibody
Application
WB analysis of extracts from various cells using PRG2 antibody.
Application Notes
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200:
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.