Rabbit Polyclonal antibody to PRG2 (bone marrow proteoglycan)The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human PRG2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
BMPG antibody MBP antibody MBP1 antibody MGC14537 antibody PRG2 antibody eosinophil granule major basic protein antibody proteoglycan 2 preproprotein antibody bone marrow proteoglycan antibody bone-marrow proteoglycan antibody eosinophil major bas
Molecular Weight(MW)
25 kDa (note) (5)
Application
Application
Immunohistochemical analysis of paraffin-embedded human hepatoma, using PRG2 antibody at 1:500 dilution.
Application
Sample (30 ug of whole cell lysate) A: Jurkat B: K562 C: THP-1 D: HL-60 12% SDS PAGE diluted at 1:1000
Positive Control
Jurkat , K562 , THP-1 , HL-60
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.