Application
Immunohistochemistry of AGR2 in human small intestine tissue with AGR2 antibody at 5 μg/ml.Application
Immunofluorescence of AGR2 in human small intestine tissue with AGR2 antibody at 20 μg/ml.Application
Western blot analysis of AGR2 in Hela cell lysate with AGR2 antibody at (A) 1 and (B) 2 μg/mL| Product Name | AGR2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AGR2 Antibody: AG2, GOB-4, HAG-2, XAG-2, PDIA17, HEL-S-116, AG2, UNQ515/PRO1030, Anterior gradient protein 2 homolog, HPC8, AG-2 |
| Product description | AGR2 Antibody: AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).1) Zhang JS, Gong A, Cheville JC, et al. AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer. Genes Chromosomes Cancer 2005; 43:249-59. |
| Immunogen | Rabbit polyclonal AGR2 antibody was raised against a 17 amino acid peptide near the amino terminus of human AGR2. The immunogen is located within the first 50 amino acids of AGR2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| AGR2 antibody can be used for detection of AGR2 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | AGR2 |
|---|---|
| Alternative Names | AGR2 Antibody: AG2 GOB-4 HAG-2 XAG-2 PDIA17 HEL-S-116 AG2 UNQ515/PRO1030 Anterior gradient protein 2 homolog HPC8 AG-2 |
| Molecular Weight(MW) | 19 kDa |
| Sequence Similarities | 2) Cat. No. 11-801 - Human Small Intestine Tissue Slide |
| Tissue Specificity | Two isoforms of AGR2 exists as a result of alternative splicing event. |
Application
Immunohistochemistry of AGR2 in human small intestine tissue with AGR2 antibody at 5 μg/ml.
Application
Immunofluorescence of AGR2 in human small intestine tissue with AGR2 antibody at 20 μg/ml.
Application
Western blot analysis of AGR2 in Hela cell lysate with AGR2 antibody at (A) 1 and (B) 2 μg/mL| Positive Control | 1) Cat. No. 1201 - HeLa Cell Lysate |
|---|---|
| Application Notes | AGR2 antibody can be used for detection of AGR2 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | AGR2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | AGR2 Antibody is supplied in PBS containing 0.02% sodium azide. |
