Mouse monoclonal antibody [1A6] to Progesterone ReceptorThis gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Jan 2011]
Immunogen
Synthetic peptide corresponding to a site of predicted high antigenicity on the human progesterone receptor.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1A6
Host Species
Mouse
Tested Applications
IHC-P
Western Blotting: 1/25 - 1/50:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
PGR progesterone receptor PR NR3C3
Target
Progesterone Receptor
Tissue Specificity
This antibody recognizes the human progesterone receptor.
Application
Application
IHC-P analysis of breast cancer biopsy tissue using Progesterone Receptor antibody. Heat mediated antigen retrieval using citrate buffer pH6.0.
Application Notes
Western Blotting: 1/25 - 1/50:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.