Application
Immunohistochemical analysis of paraffin-embedded human infiltrating ductal carcinoma tissue(left) and simple carcinoma of breast cancer tissue(right), showing nuclear localization using anti-PR antibody with DAB staining.Application
Western blot analysis using anti-PR monoclonal antiobdy against PR recombinant protein(1).| Product Name | Progesterone Receptor antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [2F12B4,2F12H2] to PRThis gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Jan 2011] |
| Immunogen | The immunogen corresponding to PR expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 2F12B4,2F12H2 |
| Host Species | Mouse |
| Tested Applications | ELISAIHCIHC-PWB |
| ELISA: 1/10000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PGR PR NR3C3 |
|---|---|
| Target | PR |
| Cellular Localization | Nucleoplasmic shuttling is both homone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases. Mainly nuclear. |
Application
Immunohistochemical analysis of paraffin-embedded human infiltrating ductal carcinoma tissue(left) and simple carcinoma of breast cancer tissue(right), showing nuclear localization using anti-PR antibody with DAB staining.
Application
Western blot analysis using anti-PR monoclonal antiobdy against PR recombinant protein(1).| Application Notes | ELISA: 1/10000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4℃, for long term storage, store at -20℃. |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
