Application
Immunofluorescence analysis of paraformaldehyde-fixed A549, using Progesterone receptor antibody at 1:200 dilution.Application
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using Progesterone receptor antibody at 1:100 dilution.Application
Immunohistochemical analysis of paraffin-embedded human breast cancer using Progesterone Receptor antibody diluted at 1:500. Representative data showing negative staining in PR-negative breast cancer (left) and nuclear staining in PR-positive breast cancer (right).| Product Name | Progesterone Receptor antibody , N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Progesterone receptor (progesterone receptor)This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Progesterone Receptor. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-P |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Pig, ChimpanzeeMouse (83%), Rat (92%), Pig (92%), Chimpanzee (93%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | NR3C3 antibody PR antibody PGR antibody progesterone receptor antibody nuclear receptor subfamily 3 group C member 3 antibody |
|---|---|
| Target | Progesterone receptor |
| Molecular Weight(MW) | 99 kDa (note) |
| Cellular Localization | Nucleus , Cytoplasm , Isoform A: Nucleus |
Application
Immunofluorescence analysis of paraformaldehyde-fixed A549, using Progesterone receptor antibody at 1:200 dilution.
Application
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using Progesterone receptor antibody at 1:100 dilution.
Application
Immunohistochemical analysis of paraffin-embedded human breast cancer using Progesterone Receptor antibody diluted at 1:500. Representative data showing negative staining in PR-negative breast cancer (left) and nuclear staining in PR-positive breast cancer (right).| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
