| Product Name | Properdin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [10-24] to ProperdinThis gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009] |
| Immunogen | Purified Properdin from human serum |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 10-24 |
| Host Species | Mouse |
| Tested Applications | ELISAIHC-F |
| IHC-F:1:50~1:100 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PFC BFD PROPERDIN PFD CFP |
|---|---|
| Target | Factor P |
| Tissue Specificity | This antibody recognizes human . It does not inhibit function of Properdin. |
| Application Notes | IHC-F:1:50~1:100 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Borate buffered saline containing 0.09% Sodium Azide (NaN3) |
