Application
Immunohistochemistry of Prosapip1 in rat brain tissue with Prosapip1 antibody at 2.5 ug/ml.Application
Western blot analysis of Prosapip1 in SK-N-SH cell lysate with Prosapip1 antibody at 1 ug/ml.Application
Immunofluorescence of Prosapip 1 in rat brain tissue with Prosapip 1 antibody at 20 μg/mL.Application
Western blot analysis of Prosapip1 in SK-N-SH cell lysate with Prosapip1 antibody at 1 μg/mL.| Product Name | Prosapip1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Prosapip1Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3’s PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed ‘Fezzins’. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Prolinerich synapseassociated proteininteracting protein1 Proline-rich synapse-associated protein-interacting protein 1 Prosapip1 Prolinerich synapseassociated proteininteracting protein 1 |
|---|---|
| Target | Prosapip1 |
| Tissue Specificity | This antibody is specific for Prosapip1 |
Application
Immunohistochemistry of Prosapip1 in rat brain tissue with Prosapip1 antibody at 2.5 ug/ml.
Application
Western blot analysis of Prosapip1 in SK-N-SH cell lysate with Prosapip1 antibody at 1 ug/ml.
Application
Immunofluorescence of Prosapip 1 in rat brain tissue with Prosapip 1 antibody at 20 μg/mL.
Application
Western blot analysis of Prosapip1 in SK-N-SH cell lysate with Prosapip1 antibody at 1 μg/mL.| Positive Control | Blocking Peptide: |
|---|---|
| Application Notes | ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
