Application
Western blot analysis of Aldh3A1 in human stomach lysate with Aldh3A1 antibody at (A) 1 and (B) 2 μg/mL.| Product Name | Aldh3A1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Aldh3A1 Antibody: ALDH3, ALDHIII, ALDH3, Aldehyde dehydrogenase, dimeric NADP-preferring |
| Product description | Aldh3A1 Antibody: Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorbtion of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1.1) Vasiliou V and Pappa A. Polymorphisms of human aldehyde dehydrogenases. Consequences for drug metabolism and disease. Pharmacology2000; 61:192-8. |
| Immunogen | Aldh3A1 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of the human Aldh3A1. The immunogen is located within the last 50 amino acids of Aldh3A1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| Aldh3A1 antibody can be used for detection of Aldh3A1 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ALDH3A1 |
|---|---|
| Alternative Names | Aldh3A1 Antibody: ALDH3 ALDHIII ALDH3 Aldehyde dehydrogenase dimeric NADP-preferring |
| Tissue Specificity | At least two isoforms of Aldh3A1 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A2. |
Application
Western blot analysis of Aldh3A1 in human stomach lysate with Aldh3A1 antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1319 - Human Stomach Tissue Lysate |
|---|---|
| Application Notes | Aldh3A1 antibody can be used for detection of Aldh3A1 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Aldh3A1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Aldh3A1 Antibody is supplied in PBS containing 0.02% sodium azide. |
