Western blot analysis of AMHR2 using rabbit polyclonal AMHR2 Antibody (N-term R80) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AMHR2 gene (Lane 2).
Anti-Muellerian hormone type-2 receptor, Anti-Muellerian hormone type II receptor, AMH type II receptor, MIS type II receptor, MISRII, MRII, AMHR2, AMHR, MISR2
Product description
The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.1) Picard, J.Y., et al., J. Soc. Biol. 196(3):217-221 (2002).
Immunogen
This AMHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-91 amino acids from the N-terminal region of human AMHR2.
Anti-Muellerian hormone type-2 receptor Anti-Muellerian hormone type II receptor AMH type II receptor MIS type II receptor MISRII MRII AMHR2 AMHR MISR2
Molecular Weight(MW)
63 kDa
Sequence Similarities
Predicted species reactivity based on immunogen sequence: Mouse
Western blot analysis of AMHR2 using rabbit polyclonal AMHR2 Antibody (N-term R80) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AMHR2 gene (Lane 2).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.