| Product Name | ANGPTL7 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Angiopoietin-like Protein 7; Cornea-derived Transcript 6 Protein |
| Product description | ANGPTL7 is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/ beta-catenin signaling pathway, and is a pharmacogenomics target in the fields of oncology and regenerative medicine. Overexpression of ANGPTL7 increases collagen expression and might exert a pathogenic role in glaucoma. |
| Immunogen | Coiled-coil domain of recombinant human ANGPTL7. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | ANGPTL7 |
|---|---|
| Alternative Names | Angiopoietin-like Protein 7 Cornea-derived Transcript 6 Protein |
| Tissue Specificity | Recognizes the coiled-coil domain of human ANGPTL7 and the ANGPTL7 full length protein. Weakly cross-reacts with the coiled-coil domains of human ANGPTL2, ANGPTL3, ANGPTL4 and ANGPTL5. Weakly cross-reacts with ANGPTL6 and ANGPTL3 full length protein. Does not cross-react with the fibrinogen like domain of ANGPTL7. |
| Application Notes | ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least 6 months after receipt when stored at -20˚C. |
| Storage Buffer | Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives. |
